Biomedical engineering · Wales

Closer to
the signal.

Wearable hardware. Physiological signals.
Machine learning.

We develop sensing platforms and analysis methods for medical research, and help medical technology teams build theirs.

Physiology, in detailECG + PPG
Aligned ECG and PPG waveforms Three illustrative heartbeats share a time axis. Each ECG has a P wave, QRS complex and T wave. The corresponding PPG pulse follows it. An arrow marks pulse arrival time from the middle ECG R peak to the foot, or onset, of its corresponding PPG pulse. ECGPPG R peakPulse footPulse arrival time (PAT)R peak to pulse foot TIME
Illustrative waveforms. Landmark visibility varies with recording conditions and physiology.PAT includes the pre ejection period.
From the sensor to the modelHardware development Research Consultancy

01 / Expertise

The whole measurement chain.

A useful model starts with a useful measurement. We work across the hardware, the physiology and the analysis, so decisions at each stage make sense together.

01

Wearable hardware

Sensor selection, embedded systems and physiological data acquisition. We develop wearable platforms and the tools needed to capture and inspect their recordings.

Sensor integration · Embedded C · Prototyping

02

Signal processing

Understanding what is in a recording, and what can be trusted. Our work covers signal quality, beat detection, waveform features and analysis across multiple sensors.

PPG · ECG · Multimodal analysis

03

Machine learning

Machine learning and deep learning for biomedical data. We build processing and modelling pipelines, from dataset preparation and feature engineering to model evaluation.

Biomedical time series · ML · Deep learning

02 / Our hardware

More of the signal.
More room to investigate.

Research needs more than heart rate and beat intervals. It needs access to the underlying signals and a clear account of how they have been processed.

We are developing wearable sensing hardware that gives researchers greater freedom to explore physiological data. Our aim is to make raw recordings available where needed and provide a clear account of any processing applied, so researchers can understand their measurements and choose how to use them.

That flexibility extends to the analysis. Researchers can use their own methods or work with us on preprocessing, signal quality assessment and further analysis, with an approach suited to their study and a documented processing chain.

To make these capabilities useful in practice, we are designing around the people and services that will use them. Clinical workflows, the needs of clinicians and integration with healthcare services are considered from the outset, including how recordings are collected, reviewed and used within a study or care pathway.

Platform in development
The research workflowW / 01
01

Capture

Physiological and movement signals

02

Inspect

Signal quality and measurement behaviour

03

Analyse

Waveform features and relationships

04

Model

Reproducible machine learning pipelines

Hardware and analysis, developed together.

03 / Consultancy

Bring us the technical question.

We work with medical technology companies and research teams on specific engineering problems and broader development projects.

01

Sensing and technical feasibility

02

Signal processing and data quality

03

Machine learning and deep learning pipelines

04

Experimental analysis and prototype evaluation

04 / Research direction

What can a pulse
tell us about
vascular function?

We are interested in the detail of the PPG waveform and what it may reveal about cardiovascular physiology.

We have a particular interest in endothelial function. Our research direction explores whether PPG and complementary physiological measurements can provide useful information about vascular function, and how those measurements could be evaluated in clinical research.

This means connecting wearable measurements with physiological questions and evaluating them against appropriate reference methods. Applications in pregnancy and pre eclampsia are one area of interest within that broader work.

Discuss a research collaboration

A closer look / PPG morphology

Features within a single pulse.

Pulse shape offers more to investigate than heart rate alone. Here, Δt marks the time between the systolic and diastolic peaks.

The notch and secondary peak are not distinct in every recording. These landmarks describe waveform shape, rather than a direct measurement of endothelial function.

Read the review on PPG and vascular ageing
PPG pulse morphology An enlarged illustrative pulse rises from its foot to a systolic peak, falls to a dicrotic notch, rises to a smaller diastolic peak and returns to baseline. Delta t measures the interval between the two peaks. Δt · systolic to diastolic peakSystolic peakDiastolic peakDicrotic notch
Illustrative pulse. Timing and amplitude are not to scale.

05 / About Wearalyze

Based in Wales.
Built on research.

Wales, United Kingdom

Wearalyze is a Welsh biomedical technology company founded by Dr David O’Connor, an engineer and researcher working across sensors, physiological monitoring and data analysis.

David’s experience includes wearable cardiovascular monitoring at Swansea University on projects funded by Wellcome Leap, and research and development at Cyden in a regulated medical device environment.

At Swansea University, he also worked with Boston Scientific on imaging and analysis of transcatheter aortic valve replacement (TAVR) devices, using stereo imaging and digital image correlation to measure their displacement and strain.

His background spans embedded sensing, cardiovascular modelling, experimental methods and biomedical data pipelines. Wearalyze brings that experience together through its own technology development and consultancy.

EngDSwansea University
Hardware + analysisAcross research and industry

Let’s talk

What are you
working on?

Tell us about your device, your data or the question you are trying to answer. We welcome consultancy enquiries and research collaborations.

contact@wearalyze.com